> For the complete documentation index, see [llms.txt](https://cmo-ci.gitbook.io/access-quality-control-v1/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://cmo-ci.gitbook.io/access-quality-control-v1/meta-information-per-sample.md).

# Meta information per sample

Overview of library and coverage information for the current set of samples run through ACCESS assay

![](https://2763969089-files.gitbook.io/~/files/v0/b/gitbook-legacy-files/o/assets%2F-M52gq1rRSDQOKMQGEuR%2F-M9Z39Nd7c6cJRknLQBm%2F-M9Z55bruZykVtLxd0It%2FScreen%20Shot%202020-06-11%20at%2011.55.52%20AM.png?alt=media\&token=24dfca99-aa22-435d-a420-a80902855fd7)

#### **Technical Method**

* Tool Used: plots\_module.r
* Input: 
  * title\_file.txt
  * coverage\_agg.txt
  * average\_coverage\_across\_exon\_targets\_duplex\_A.txt
* Output: N/A

#### **Interpretation**

* Library input should be \~5-20ng for ctDNA, \~200ng for buffy coats (or the maximum amount available if these thresholds can’t be met)
* Capture input should be \~500ng or maximum available after library generation
* Expected range of coverage values:
  \*
  * Raw coverage A panel: 
    * ctDNA: \~ 15000x-20000x
    * Buffy Coat: \~ 500x-1000x
  * Raw coverage B panel: 
    * ctDNA: \~ 1000x-1,500x
    * Buffy Coat: \~ 500x-1000x
  * Duplex coverage A panel: 
    * ctDNA: \~ 500x-2000x 
    * Buffy Coat: \~ 10x-50x

{% hint style="info" %}
**Note:** Samples that don’t meet the library input criteria will have lower coverage
{% endhint %}

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